Volume : VII, Issue : IV, April - 2017

Clinical Characteristics of Guillain–Barre Syndrome in children: A single center study

Abhay S Bagul, Vinit M Warthe, Jaykumar Patel

Abstract :

 Introduction: The Guillain–Barre syndrome (GBS) is an immune mediated acute polyradiculoneuritis and incidence of GBS ranges from 0.6 to 4.0/100,000 population. Now, GBS is most common cause of acute flaccid paralysis. Clinical characteristics of GBS in different regions and in different ages might be distinct. Hence, this study is planned to study clinical characteristics of GBS in children.

Methods: This was prospective observational study conducted from November 2014 to October 2016 and total 28 children enrolled in the study. A detailed history, clinical examination and cereospinal fluid examination of enrolled children was done and ten patients were treated with intravenous immunoglobulin.

Results: Out of 28, 15 (53.57%) were male and 13 (46.43%) were female. Age of subjects at time of presentation varies from 1 year to 12 years with mean of 5.89 and standard deviation ±3.02. Most common antecedent event was upper respiratory tract infection (25%). Occurrence of GBS was more in monsoon 16(57.14%). Motor weakness was most common presentation. Four patients had respiratory paralysis and out of four, two were died (7.14%).

Conclusion: Occurrence of GBS was more in monsoon (June to September) in our study. Motor weakness was most common presentation and nadir of weakness was within 7(4–14) days.

 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Abhay S Bagul, Vinit M Warthe, Jaykumar Patel, Clinical Characteristics of Guillain–Barre Syndrome in children: A single center study, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾4 | April-2017


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