CLINICAL PROFILE AND OUTCOMES IN PATIENTS WITH ACUTE KIDNEY INJURY WITH AND WITHOUT UNDERLYING CO–MORBIDITIES.

Dr. Vrushali R. Wagh; Dr. Shilpa S. Sule; Dr. Khalid I. Khatib; Dr Dileep B. Kadam

Volume : IX, Issue : VII, July - 2019

CLINICAL PROFILE AND OUTCOMES IN PATIENTS WITH ACUTE KIDNEY INJURY WITH AND WITHOUT UNDERLYING CO–MORBIDITIES.

Dr. Vrushali R. Wagh, Dr. Shilpa S. Sule, Dr. Khalid I. Khatib, Dr Dileep B. Kadam

Abstract :

Aims and Objectives: To compare clinical profile and outcome in patients with acute kidney injury with respect to underlying co–morbidities. Material and Methods: This is retrospective study of 30 patients with AKI admitted in SKNMC and GH between Jan 2018 to July 2018.Patients age>18 years were included and those who are already known case of chronic kidney disease were excluded from study. Results: A total number of 30 cases with Acute Kidney Injury (AKI) admitted to SKNMC and GH, who met the inclusion criteria, are studied. Out of 30 patients 17 patients were male and 13 patients were female. Mean age of presentation was 56.8 years. Maximum patients (46.67%) were from elderly age group. There was male predominance (M:F –1.3:1). Most common cause of AKI was found to be Prerenal (50.9%). Maximum numbers of AKI patients in present study were oligouric (76.67%).Out of total AKI patients 22 had underlying comorbidity (Gr.A) and 8 had no co–morbidity (Gr. B). Patients with co–morbidities, 36.36% had DM, 27.27% had HTN, and 22.73% had chronic liver disease, 9.09% had IHD and 4.55% had COPD. In Gr.A 91% patients were more than 50 yrs old, M: F ratio 1.5:1, 72.8% were oliguric, 54.5% required dialysis, and 86.4 % required ICU management. In Gr.B 25 % were more than 50 yrs old, M: F ratio 1:1, 87.5% were oliguric, 37.55 required dialysis, and 37.5% required ICU management. In Gr.A and Gr.B , 54.5% &75% pre–renal, 36.5% & 25% renal , 9% & 0% had post renal as a cause of AKI respectively ( P– 0.311). Morbidity (Residual Renal disease) and mortality was 50 % in Gr. A and 12.5% in Gr. B. Conclusion: Patients more than 50yrs of age with underlying co–morbidities had significant risk of developing AKI (P < 0.0003).There was significant association between presence of co morbidies and requirement of ICU (P–0.007).The outcome was worse in patients with underlying co–morbidities though not statistically significant (P–0.06).