Volume : IX, Issue : II, February - 2019

Clinical profile and survival outcomes of Ewing's sarcoma. An institutional experience.

Dr. D. Bhargavi, Dr B. Manilal

Abstract :

Background: To analyze the disease characteristics and survival outcomes of Ewing’s sarcoma family of tumors. Methods: In this retrospective study, data analyses of Ewing’s sarcoma patients between 2013 to 2016 were analyzed. Age, sex, stage, site, skeletal/extra skeletal tissue of origin, and treatment details were recorded. Complications during chemotherapy were recorded. Survival outcomes were analyzed. Results: Out of the 42 cases, 54.8% were males. The mean age at presentation was 22.7±13.47 years. Majority of patients (66.7%) had limited disease at presentation. Most of the patients (57.1%) had extra skeletal Ewing’s sarcoma. VAC/IE and VAC only chemotherapy was given for limited and extensive disease respectively. Only 7 patients received planned cycles of chemotherapy in the limited stage. Symptomatic cardiac failure was observed in 3 patients. Two patients developed deep vein thrombosis of leg during therapy. One patient died due to feile neutropenia. Two year PFS and OS are 33.3 % and 40% respectively for the whole group. Conclusion: Extra skeletal involvement comprises a larger number of cases as compared to skeletal Ewing’s sarcoma. Survival outcomes are poor owing to poor compliance to the therapy

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

CLINICAL PROFILE AND SURVIVAL OUTCOMES OF EWING'S SARCOMA. AN INSTITUTIONAL EXPERIENCE., Dr.D. BHARGAVI, Dr B.MANILAL INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-2 | February-2019

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