Clinical profile of patients with Chronic liver disease in North west Tamilnadu

Dr.Caroline Selvi K; Dr.Aravind.A; Dr. Kandasamy alias Kumar. E

Volume : VII, Issue : VI, June - 2017

Clinical profile of patients with Chronic liver disease in North west Tamilnadu

Dr. Caroline Selvi K, Dr. Aravind. A, Dr. Kandasamy Alias Kumar. E

Abstract :

Background:Chronic liver disease (CLD) and its sequelae form a major part of gastroenterological workload in any large hospital.Over the years, with the advent of newer techniques for identification of viruses, biochemical markers, and newer histopathological methods, it is now possible to enlarge the classification and attach more informative labels to such cases. Methods: Study Design : Descriptive study .The study was conducted in Government Mohan Kumarmangalam Medical college Hospital, Salem, during the period January 2014 to Feuary 2017. 100 consecutive adult patients admitted to the male and female wards of Medical Gastroenterology diagnosed to have CLD were included in the study.Results:The 100 patients of chronic liver disease could be classified on clinicopathological as well on etiological basis. On clinic pathological grounds the patients could be divided asfollows:Decompensated cirrhosis :60 Compensated cirrhosis: 24.NASH:3.HCC:3.CAH:10.Based on the evaluation of viral markers, alcoholic intake, previous blood transfusion and copper studies in a few cases, the patients could be grouped into several categories as follows:GroupA: Positive for only alcohol:23;GroupB:Positive for only HBV:22;GroupC:Positive for only HCV:3Group D: Postive for both HBV & alcohol:15;Group E : Positive for both HCV & alcohol: 1;Group F: NASH :3;Group G: Cryptogenic :28;Group H: Miscellaneous – Wilson’s Disease:5.. Conclusion: Chronic liver disease is a major health problem in this area.60 out of 100 patients with CLD were related to Ethanol and HBV either singly or in combination.The incidence of HCV infection is very low in this part of the world (4%).A sizeable proportion (28%) belongs to the group of cryptogenic cirrhosis which calls for a lot of research in this sphere to detect new viruses or environmental factors responsible.The prevalence of NASH in patients with CLD is 3%.