CLINICO–PATHOLOGICAL STUDY ON EVALUATION OF IDIOPATHIC THROMBOCYTOPENIC PURPURA IN TERTIARY CARE HOSPITAL OF TELANGANA

Madhukar Reddy Kadaru; Raja Kumar K

Volume : IX, Issue : VII, July - 2019

CLINICO–PATHOLOGICAL STUDY ON EVALUATION OF IDIOPATHIC THROMBOCYTOPENIC PURPURA IN TERTIARY CARE HOSPITAL OF TELANGANA

Madhukar Reddy Kadaru, Raja Kumar K

Abstract :

OBJECTIVES: The study was designed to co–relate the pathological findings with clinical manifestations of ITP and to validate the diagnosis of ITP. METHODS: A retrospective and prospective hospital based study was carried out over a period of three years (2017–2019). RESULTS: Out of 57cases,19 cases(33%) occurred in the age range of 0–20 years, 27cases(48%) in the range of 21–40 years and 11 cases (19%) in the range of 41–60 years. 39 cases(68%) occurred in male population and 18 cases (32%) in female population. The most common presentation was with petechiae in 21 cases(39%). 19 cases(35%) had a platelet count of less than 25,000 and 34 cases(65%) had a count between 25,000 and 50,000. A Mean Platelet Volume(MPV) value of 11–14 fL was seen in 78% of the cases . Platelet Distribution Width(PDW) of 15–17 fL was seen in 81% of cases. INTERPRETATION AND CONCLUSION: No single laboratory result or clinical finding establishes a diagnosis of ITP; it is a diagnosis of exclusion. Bone Marrow Aspiration(BMA) is not needed for children with typical features of ITP ;however BMA helps in diagnosis of ITP in patients who present with atypical features.