Volume : VIII, Issue : XII, December - 2018

CLINICOPATHOLOGICAL CORRELATION OF TRIPLE NEGATIVE AND HER 2 POSITIVE BREAST CANCERS

Dr. Prudhvi Gaddam, Dr. Roshan M, Dr. Nishitha Shetty

Abstract :

 Breast cancer is presently the most common cancer in women. [1] Breast cancer is a heterogeneous disease. It is classified according to its histologic pattern into various groups having differing prognosis. While treating the patient, the factors taken into account are histologic type, modified Bloom Richardson score, TNM stage, estrogen and progesterone receptors (ER and PR) status, and overexpression of human epidermal growth factor receptor 2 (Her2). Studying the clinicopathological characters of different types of east tumors helps in understanding the course of the disease and to stratify the treatment protocols. and there are very few studies available correlating the clinicopathological features of triple negative and her 2 positive east tumors in Indian patients. To compare the clinical features and post–surgery pathological parameters among women with “triple–negative” and her 2 positive  east cancer.

Materials and Methods

This was a retrospective study of patients who have attended  FMMCH oncology department in the past 1 year and with diagnosis of carcinoma east,belonging to either triple negative or HER 2 positive group. Clinical records of the cases will retrieved and analyzed. The data will be collected from patients records who had attended services in Father Muller medical college, Oncology department,  who have  satisfied the inclusion criteria

Results Luminal A carcinoma was the most common (97 cases 32.22%), followed by TNBC (45 cases, 14.5%) and HER2/neu positive carcinomas (92 cases 30.7%).  

 

Conclusion:  TNBC were mostly high–grade .with poor prognosis .

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

CLINICOPATHOLOGICAL CORRELATION OF TRIPLE NEGATIVE AND HER 2 POSITIVE BREAST CANCERS , DR. PRUDHVI GADDAM, DR.ROSHAN M, DR. NISHITHA SHETTY , INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8|Issue-12| December-2018


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