Volume : VII, Issue : X, October - 2017

Coagulation profile in newborns born to mothers with pregnancy induced hypertension

Shinde Pramod J, Shinde Archana P

Abstract :

 Background :

Pregnancy induces complex changes concerned with hemostasis .Severe hypertension in pregnant women before 36 weeks of gestation is a multisystem disease & is a threat to the wellbeing of mother as well as her child. Alteration in coagulation profile is the most common cause of haemorrhagic diathesis in newborn born to mothers with pregnancy induced hypertension. So the objective of the study was to study coagulation parameters in newborns born to mothers with PIH in different subgroups. Methods: The effects of pregnancy induced maternal hypertension on the coagulation profile of newborn were studied in 80 cases compå the values with that of infants born to normotensive mothers.Results:  All the neonates born to mothers with severe pre–eclampsia & eclampsia were preterm neonates. The values of Prothrombin Time, Partial Thromboplastin Time with Kaolin, Thrombin Time, Fiinogen Degradation Products were significantly raised and Fiinogen and Platelet count were reduced significantly in both term and preterm test groups as compared to controls. Conclusion:  Both term & preterm neonates of PIH mothers are at increased risk of developing thrombocytopenia & coagulation defects. Neonates of pre eclamptic and eclamptic mothers had thrombocytopenia & coagulation defects. Thrombocytopenia might be the earliest manifestation of neonatal disease. The derangement in coagulation parameters was more marked with increasing severity of PIH.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Shinde Pramod J, Shinde Archana P, Coagulation profile in newborns born to mothers with pregnancy induced hypertension, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-7 | Issue-10 | October-2017

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