Volume : V, Issue : IV, April - 2015

Comparative Ceftaroline Activity Tested Against Staphylococcus Aureus Associated with Acute Bacterial Skin and Skin Structure Infection from A Tertiary Care Center

Dr. Umamageswari S. S. M. , Dr. S. Habeeb Mohammed, Dr. Shameem Banu, Dr. Jayanthi S.

Abstract :

 Methicillin resistant Staphylococcus aureus (MRSA), commonest cause of acute bacterial skin and skin 

structure infection (ABSSSI) has only limited treatment options like vancomycin, Linezolid and teicoplanin. 
Staphylococcus aureus with reduced susceptibilities to vancomycin is developing nowadays among nosocomial infection. A newest cephalosporin – Ceftaroline has received FDA approval for the treatment of ABSSI recently has unique 
activity against MRSA. The aim of the study is to know the prevalence of Staphylococcus aureus in ABSSSI patients and 
to evaluate the in vitro activity of Ceftaroline, in comparison with other drugs. Minimum Inhibitory Concentration for 
vancomycin and Ceftaroline were determined by E–test strips. Out of 235 Staphylococcus aureus isolated from ABSSSI 
patient 32% were MRSA. No vancomycin resistant strain isolated in our study. In vitro, Ceftaroline control the growth of 
MRSA very effectively at 2mg/ml itself. Ceftaroline is a most welcomed drug in the treatment of MRSA.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Umamageswari S. S. M., Dr. S. Habeeb Mohammed, Dr. Shameem Banu, Dr. Jayanthi S. Comparative Ceftaroline Activity Tested Against Staphylococcus Aureus Associated with Acute Bacterial Skin and Skin Structure Infection from A Tertiary Care Center Indian Journal of Applied Research, Vol.5, Issue : 4 April 2015


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