Volume : V, Issue : VII, July - 2015

COMPARATIVE EVALUATION OF BUPIVACAINE PLAIN VERSUS BUPIVACAINE WITH DEXMEDETOMIDINE IN SPINAL ANAESTHESIA FOR VAGINAL HYSTERECTOMY CASES

Dr. Dhananjay Batwara, Dr. Urmi Dave, Dr. Vandana Parmar, Dr. Pratik Doshi, Dr. Deepa Gondalia, Dr Poonam Nehra

Abstract :

 Background: The study aimed to compare the analgesic efficacy and recovery characteristics of Fentanyl and Butorphanol under TIVA (Total Intravenous Anesthesia) for laparoscopic cholecystectomy and find out the better analgesic along with Propofol. Patients and methods: Seventy two patients of ASA grade I and II of either sex in the age group of 20–60 years undergoing laparoscopic cholecystectomy were allocated to one of the two groups of 36 each. Group I received Inj. Fentanyl in the doses of 2 µg/kg while patients in group II received Butorphanol in doses of 25µg/kg. All the patients were induced with Inj. propofol 2 µg/kg and intubated with 100 µg/kg Vecuronium. Anaesthesia was maintained by Oxygen, Nitrous oxide and Propofol. Intra–operative hemodynamic parameters (HR, MAP) were noted. Recovery time, post operative sedation, duration of analgesia using visual analogue pain score and post operative complications were noted. Results were compared among the groups using the unpaired t test and chi square test. In all cases, p < 0.05 was considered statistically significant. Results: Demographic characteristics as well as duration of surgery, baseline pulse rate, systolic blood pressure and diastolic blood pressure were comparable in both the groups. Intraoperative and post operative hemodynamics in butorphanol group were more stable when compared to Fentanyl group. All the patients in butorphanol group were sedated but arousable and had analgesia for 3 hours post operatively while in case of Fentanyl group, patients required rescue analgesia within 30 minutes after extubation and patients were not sedated. No significant intra operative complication was observed in both the groups. The incidence of nausea and vomiting was slightly more in butorphanol group. No incidence of respiratory depression was noted in both the groups. Conclusion: Both Butorphanol and Fentanyl are cardio stable. Less haemodynamic variations are observed in the Butorphanol group. Recovery time in Butorphanol group was more (5.86 min) when compared to that in Fentanyl group (3.33 min) which is not clinically significant. Post operative sedation and analgesia remained for longer duration in Butorphanol group. Thus we can conclude that butorphanol is better alternative to Fentanyl in terms of haemodynamic stability and prolonged analgesia

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Dhananjay Batwara, Dr. Urmi Dave, Dr. Vandana Parmar, Dr. Pratik Doshi, Dr. Deepa Gondalia, Dr Poonam Nehra Comparative Evaluation of Bupivacaine Plain Versus Bupivacaine with Dexmedetomidine in Spinal Anaesthesia for Vaginal Hysterectomy Cases Indian Journal of Applied Research, Vol.5, Issue : 7 July 2015

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