Volume : VII, Issue : VIII, August - 2017

Comparative evaluation of clinical and orthopantamogram (OPG) findings in Oral Squamous Cell Carcinoma

Dr. Swapnil C. Mohod, Dr. Rahul R. Bhowate, Dr. Vidya K. Lohe, Dr. Suwarna B. Dangore

Abstract :

 Worldwide, head and neck cancer is the sixth most common cancer for men and women, and the third most common in developing nations. ADDIN ZOTERO_ITEM CSL_CITATION {"citationID":"5h6CRFV2","properties":{"formattedCitation":"(1)","plainCitation":"(1)"},"citationItems":[{"id":19,"uris":["http://zotero.org/users/local/nsv95B4m/items/TNDIWUBR"],"uri":["http://zotero.org/users/local/nsv95B4m/items/TNDIWUBR"],"itemData":{"id":19,"type":"article–journal","title":"Imaging of Oral Cavity Squamous Cell Carcinoma","container–title":"Oral and Maxillofacial Surgery Clinics of North America","page":"445–463","volume":"18","issue":"4","source":"CrossRef","DOI":"10.1016/j.coms.2006.06.011","ISSN":"10423699","language":"en","author":[{"family":"Aulino","given":"Joseph M."},{"family":"Strother","given":"Megan K."},{"family":"Shipman","given":"Jason L."}],"issued":{"date–parts":[["2006",11]]}}}],"schema":"https://github.com/citation–style–language/schema/raw/master/csl–citation.json"} (1) The disproportionately higher prevalence of oral cancer in India as one of the fifth leading cancer in either sex are related to the use of tobacco in various forms, consumption of alcohol and low socioeconomic condition related to poor hygiene, poor diet or infections of viral origin. ADDIN ZOTERO_ITEM CSL_CITATION {"citationID":"bGzDS8XV","properties":{"formattedCitation":"(2)","plainCitation":"(2)"},"citationItems":[{"id":22,"uris":["http://zotero.org/users/local/nsv95B4m/items/9W2XKJNY"],"uri":["http://zotero.org/users/local/nsv95B4m/items/9W2XKJNY"],"itemData":{"id":22,"type":"article–journal","title":"Perineural invasion in squamous cell carcinoma of the head and neck","container–title":"Archives of Otolaryngology––Head & Neck Surgery","page":"637–640","volume":"124","issue":"6","source":"PubMed","abstract":"OBJECTIVE: To determine if perineural invasion (PNI) of small nerves affects the outcome of patients with squamous cell carcinoma (SCC) of the upper aerodigestive tract.nDESIGN: Retrospective clinicopathological study of patients with at least 2 years of follow–up and with negative margins and no prior, synchronous, or metachronous SCC.nSETTING: Academic otolaryngology department.nPATIENTS: One hundred forty–two patients who had SCC of the oral cavity, oropharynx and hypopharynx, or larynx resected between 1981 and 1991.nINTERVENTION: Surgery with or without adjuvant therapy.nMAIN OUTCOME MEASURES: Local recurrence was examined with respect to PNI, nerve diameter, and microvascular or microlymphatic invasion. Perineural invasion was correlated with lymph node metastasis, extracapsular spread, and survival.nRESULTS: Perineural invasion of nerves less than 1 mm in diameter was present in 74 patients, lymphatic invasion in 53, and vascular invasion in 9. Perineural invasion was significantly associated with local recurrence (23% for PNI vs 9% for no PNI; P=. 02), and disease–specific mortality (54% mortality for PNI vs 25% for no PNI; P<.001). With extralaryngeal tumors, PNI was associated with nodal metastasis (73% vs 46%; P=.03). Perineural invasion was not associated with extracapsular spread (P=.47). Microvascular invasion, lymphatic invasion, and nerve diameter were not significantly related to local recurrence.nCONCLUSIONS: Perineural invasion of small nerves is associated with an increased risk of local recurrence and cervical metastasis and is, independent of extracapsular spread, a predictor of survival for patients with SCC of the upper aerodigestive tract.","ISSN":"0886–4470","note":"PMID: 9639472","journalAbeviation":"Arch. Otolaryngol. Head Neck Surg.","language":"eng","author":[{"family":"Fagan","given":"J. J."},{"family":"Collins","given":"B."},{"family":"Barnes","given":"L."},{"family":"D‘Amico","given":"F."},{"family":"Myers","given":"E. N."},{"family":"Johnson","given":"J. T."}],"issued":{"date–parts":[["1998",6]]}}}],"schema":"https://github.com/citation–style–language/schema/raw/master/csl–citation.json"} (2)

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Swapnil C. Mohod, Dr. Rahul R. Bhowate, Dr. Vidya K. Lohe, Dr. Suwarna B. Dangore, Comparative evaluation of clinical and orthopantamogram (OPG) findings in Oral Squamous Cell Carcinoma, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾8 | August‾2017

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