COMPARATIVE EVALUATION OF INTRAVENOUS DEXMEDETOMIDINE AND INTRAVENOUS FENTANYL TO ATTENUATE PRESSOR RESPONE DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

Tripti Nagdev; Smita Joshi

Volume : VIII, Issue : X, October - 2018

COMPARATIVE EVALUATION OF INTRAVENOUS DEXMEDETOMIDINE AND INTRAVENOUS FENTANYL TO ATTENUATE PRESSOR RESPONE DURING LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION

Tripti Nagdev, Smita Joshi

Abstract :

Introduction: Laryngoscopy and Endotracheal Intubation is the gold standard for airway management.We used iv dexmedetomidine 1µg/kg and iv fentanyl 2µg/kg. Aim:To compare attenuation of pressor response and compare the effect of maintaining the haemodynamic stability during laryngoscopy and endotracheal intubation. Methods and Materials :15 to 65 years of ASA grade I and II posted for surgery.Patients were selected randomly and allocated into Group D: (n–30) received 1ug/kg of dexmedetomidine iv slowly after recording baseline vitals , diluted with normal saline to make 10ml Group F: (n–30) received 2ug/kg fentanyl iv slowly diluted with normal saline to make 10ml. Results : The demographic data was comparable, we found that ivDexmedetomidine in the dose of 1 µg/kg and iv Fentanyl 2µg/kg given ten minutes prior to induction , both attenuated the hemodynamic responses to laryngoscopy and endotracheal intubation. The attenuation of heart rate, systolic blood pressure, diastolic blood pressure and mean arterial pressure was better in group D. Conclusion : Intravenous Dexmedetomidine 1 µg/kg given 10 minutes prior to surgery was superior to intravenous Fentanyl 2µg/kg .