COMPARATIVE STUDY OF THE ANALGESIC EFFECT OF EPIDURAL DEXMEDETOMIDINE AND FENTANYL IN LOWER LIMB ORTHOPAEDIC SURGERIES

DR.M.NITTHILAM; DR.S.GEETHA

Volume : X, Issue : I, January - 2020

COMPARATIVE STUDY OF THE ANALGESIC EFFECT OF EPIDURAL DEXMEDETOMIDINE AND FENTANYL IN LOWER LIMB ORTHOPAEDIC SURGERIES

Dr. M. Nitthilam, Dr. S. Geetha

Abstract :

INTRODUCTION : Epidural anaesthesia is one of the most commonly used procedure to provide analgesia and anaesthesia for lower abdominal,perineal,lower limb surgeries.opiods have been used as an adjuvant to local anaesthetics for a longer time.Recently α–2 agonists are being used as an adjuvant to provide superior analgesia with minimal side effect AIMS: The present study aims at compå the hemodynamic,sedative and analgesic potentiating effects of epidurally administered fentanyl and dexmedetimidine when combined with ropivacaine. METHODS: 60 patients of ASA1&2 undergoing lower limb orthopaedic surgeries were randomly allocated to two groups ,RD and RF, with 25 patients in each group. Group RD received 15ml of 0.75%ropivacaine with 1µg/kg of dexmedetomidine and RF received 15ml of 0.75%ropivacaine with 1µg/kg of fentanyl. Various parameters like Heart rate,blood pressure,sedation scores at every 30 minutes,onset of sensory analgesia at T10,Time for peak sensory analgesia,onset of complete motor block,time for two segmental r egression,time for return of motor activity to omage1,duration of analgesia were recored in both groups and compared with the help of statistical tools like chi.square test,paired t–test. RESULTS: Both the study were comparable in their demographic profile,duration of surgery.onset of sensory analgesia at T10,maximum sensory analgesia and time taken to reach that level,onset of complete motor block were earlier in RD group than RF group.Duration of analgesia was also longer in RD group.patients in RD were much better sedated than RF group .Incidence of shivering,nausea was much higher in RF group while incidence of dry mouth wae higher in RD group. CONCLUSION: Thus dexmedetomidine seems to a better alternative