COMPARISION BETWEEN THE EFFECTS OF INTRATHECAL MIDAZOLAM AND FENTANYL FOR ENDOSCOPIC UROLOGICAL SURGERIES: A RANDOMISED CLINICAL TRIAL

Dr.P.S.Arunalatha; Dr.K.Anitha

Volume : IX, Issue : VIII, August - 2019

COMPARISION BETWEEN THE EFFECTS OF INTRATHECAL MIDAZOLAM AND FENTANYL FOR ENDOSCOPIC UROLOGICAL SURGERIES: A RANDOMISED CLINICAL TRIAL

Dr. P. S. Arunalatha, Dr. K. Anitha

Abstract :

INTRODUCTION : Spinal anaesthesia is a form of regional anaesthesia involving injection of a local anaesthetic into the cereospinal fluid of the patient’s subarachnoid space to anaesthetize the spinal nerve roots running through it. The local anaesthetic deposited in the subarachnoid space act on the spinal nerve roots and not on the substance of the cord. The aim of the study is to compare intrathecal fentanyl along with bupivacaine and midazolam combined with bupivacaine for the duration and the quality of spinal anaesthesia in patients undergoing endoscopic urological surgeries. MATERIALS & METHODS :A prospective randomized double blind clinical study undertaken to compare the effects of intrathecal midazolam and fentanyl as additives to intrathecal bupivacaine 0.5 % for spinal anaesthesia on 120 adult patients of SA physical status 1 & 2 in the age group of 18 to 60 years, posted for elective endoscopic urological surgeries at Government General Hospital, Kurnool from the period December 2015 to August 2017. Pulse rate, respiratory rate, arterial blood pressure and oxygen saturation were recorded every 5mins for first 30mins, and for every 15mins for next 90 mins with help of standard monitors like pulse oximetry, ECG and NIBP. The following parameters were observed – onset and duration of sensory block, onset and duration of Motor block, Two segement regression time, time for first request analgesia and any side effects associated with these drugs. CONCLUSION :The present study concludes that there were no differences in the onset and duration of sensory blockade when fentanyl 25 micrograms or midazolam 2mg was used as additive to intrathecal hyperbaric bupivacaine for spinal anaesthesia. There were no differences in the durations of onset and duration of motor blockade and effective( time for first request) analgesia when fentanyl 25 micrograms or midazolam 2mg was used as additive to intrathecal hyperbaric bupivacaine for spinal anaesthesia.