Comparison of Central Corneal Thickness Measurements by Optical Coherence Tomography, Non–Contact Specular Pachymetry and Ultrasound Pachymetry in Patients with Primary Open Angle Glaucoma

Dr. Anuradha Khodake; Dr. Puja Hingorani Bang

Volume : VII, Issue : IV, April - 2017

Comparison of Central Corneal Thickness Measurements by Optical Coherence Tomography, Non–Contact Specular Pachymetry and Ultrasound Pachymetry in Patients with Primary Open Angle Glaucoma

Dr. Anuradha Khodake, Dr. Puja Hingorani Bang

Abstract :

Purpose

To compare the central corneal thickness (CCT) measurements of non–contact methods, namely, Optical Coherence Tomography (OCT) and Non–Contact Specular Microscopy (NCSM) with those of the gold standard contact method i.e. ultrasonic pachymetry (UP) and to assess agreement between three devices in eyes with primary open angle glaucoma (POAG).

Material and methods

This study included 142 eyes (71 patients) with POAG. CCT was measuredinitially by non–contact methods followed by the contact method. An average of 3 readings was taken for each eye.

Results

The mean CCT values by OCT, NCSM, US PACHY were 507.53±34.22, 498.07±33.64 & 514.90±32.65 µm respectively. All the methods showed good reliability, significant correlation (p < 0.001).Bland Altman analysis showed good agreement.

Conclusion

All three methods are reliable, reproducible, have significantcorrelation with each other, can be used interchangeably with the application of correction formulae.