Volume : IV, Issue : XII, December - 2014

Comparison of Electroretinorgraphical Patterns in Retinitis Pigmentosa and Choloroquine Consuming Patients.

Tahmasebi, S. , Shushtarian, S. M.

Abstract :

<p>Aim: The present study was planned out to compare the electroretinorgraphical patterns in Retinitis pigmentosa & choloroquine consuming patients, and thereby to search for possible changes obtained in< /> retina of these two type of patients.< /> Method: In a descriptive–analytical study 25 patients with definite Retinitis Pigmentosa diagnosis and 25 choloroquine< /> consuming patients with certain retinal degeneration which is the side effect of long term choloroquine intake were selected. Photophic Electroretinography was recorded in two groups. The amplitude (µv) and latency (msec) of b wave of< /> ERG patterns were calculated, in these two case groups. ERG was also measured in 25 normal population with healthy< /> visual system i.e. control group. The b waves of ERG patterns in two case groups were compared with control group to< /> look for retinal changes obtained in two patient groups.< /> Results:< /> Mean amplitude (µv) and latency (msec) of ERG b were calculated in two case groups and the obtained mean values< /> were compared with the mean amplitude and latency of control group.< /> The mean amplitude ± S.D. & latency ± S.D of ERG b wave in control group were 104.8 ± 15.29 & 42.6 ± 1.78 respectively.< /> The mean amplitude ± S.D. and latency ± S.D of ERG b wave of RP patients were 32.6 ± 10.36 and 42.9 ± 2.48 respectively.< /> The difference between mean amplitude of b wave of ERG patterns is significant as for as RP patients are concerned< /> where as the mean latency is not statistically significant between case & control groups.< /> The mean amplitude ± S.D. & latency ± S.D of ERG b wave of choloroquine consuming patients were 106.2 ± 12.79< /> and 61.7 ± 13.39 respectively. The difference between mean latency of b wave of ERG is statistically significant as far< /> as choloroquine consuming patients are concerned, where as the mean amplitude is not significant between two case< /> and control groups.< /> Conclusion:< /> The result of present work is a clue that ERG pattern, mainly b wave is useful to diagnose the retinal changes take< /> place in RP and choloroquine consuming patients.</p>

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Tahmasebi, S.,Shushtarian, S.M. Comparison of Electroretinorgraphical Patterns in Retinitis Pigmentosa and Choloroquine Consuming Patients. Indian Journal of Applied Research, Vol.4, Issue : 12 December 2014

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