Cord Blood Gamma Glutamyl Transferase Activity In Neonates – With Relation To Gestational Age, Gender & Perinatal Events

PRANATHI M; KADAM NITU NARASING; GEETHA H

Volume : VII, Issue : V, May - 2017

Cord Blood Gamma Glutamyl Transferase Activity In Neonates – With Relation To Gestational Age, Gender & Perinatal Events

Pranathi M, Kadam Nitu Narasing, Geetha H

Abstract :

Introduction: A number of steroids & proteins are currently utilised as biochemical markers of foeto placental wellbeing. Among these is the gamma glutamyl transferase (GGT) activity & its importance in cord blood. Aim: To study the changes in GGT activity associated with gestational age & to correlate potential alterations in GGT activity with perinatal events. Methods: Cord blood activity of the hepatic enzyme GGT was measured in cord blood of 300 preterm & term neonates ranging from 26 to 42 weeks of gestation & compared with maternal serum enzyme activity. Results: Significant rise in GGT has been found in cord blood of neonates compared to maternal serum GGT levels. Conclusion: GGT activity in term infants with a history of perinatal events suggestive of stress was significantly higher than in term infants without such perinatal history. Few reports to date have studied the influence of perinatal factors on neonatal serum GGT.