Correlation between Fibrinogen and Mean Arterial Pressure Levels in Pre–eclamptic Women

Dr.  Prerna Mittal; Dr. Anupam Kumar Bansal

Volume : V, Issue : X, October - 2015

Correlation between Fibrinogen and Mean Arterial Pressure Levels in Pre–eclamptic Women

Dr. Prerna Mittal, Dr. Anupam Kumar Bansal

Abstract :

Fiinogen, a major heterogenous coagulation plasma protein, is involved in the hypercoagulability and the angiogenic imbalance seen in early onset of pre–eclampsia. Blood pressure is an indicator for the severity of pre–eclampsia. In this study 100 patients with pre–eclampsia were studied out of which 50 were mild and 50 were severe pre–eclamptics. They were compared with 50 healthy subjects. Subjects were of similar gestational age, body mass index (BMI) and parity matched. They were all primigravidas at third trimester of pregnancy. All studied subjects belonged to age group 28–40 years. A significant strong positive correlation was seen between fiinogen and mean arterial pressure levels (r=0.2) in mild, severe pre–eclamptics (r=0.15) and among healthy control group (r=0.05). So it is felt that it may be useful in prediction and diagnosis of the severity of pre–eclampsia.