Volume : VIII, Issue : IV, April - 2018

Correlation of antibiotic resistance and biofilm formation amongst uropathogenic E.coli

Smita K. Bawankar

Abstract :

Introduction:  Urinary tract infection (UTI) due to E.coli  is one of the most common bacterial infections. It  forms microcolonies in mucosa lining of urinary bladder known as biofilm which contribute to the development of chronic urinary infections, refractory to antibiotic therapy.

Aim: The objective of this study was to detect the production of biofilm by uropathogens isolated from UTIs and their antimicrobial susceptibility pattern.

Methods and material: A total 426 urine samples from clinically suspected UTI patients were processed by standard microbiological procedures. The isolated uropathogens were tested to biofilm production by microtitre plate  method. Antimicrobial susceptibility testing of uropathogens was done by Kirby – Bauer disc diffusion method., The data were analyzed by using SPSS version 17.0. A P–value of lessthan or equal to 0.05 was considered to be significant.

Results: The antimicrobial susceptibility pattern of biofilm producers showed high resistance to commonly used antibiotics.

Conclusions: The present study showed significant correlation between biofilm production and antibiotic resistance, so it is necessary to screen all isolates for biofilm production.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Smita K. Bawankar, Correlation of antibiotic resistance and biofilm formation amongst uropathogenic E.coli, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018

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