Correlation of Cardiovascular Autonomic Dysfunction With Increased Duration of Asthma in Gwalior Region

Dr. Virendra Verma; Dr. Dinesh Udainiya; Dr Manish Goyal

Volume : IV, Issue : V, May - 2014

Correlation of Cardiovascular Autonomic Dysfunction With Increased Duration of Asthma in Gwalior Region

Dr. Virendra Verma, Dr. Dinesh Udainiya, Dr Manish Goyal

Abstract :

CONTEXT Asthma is a respiratory system dysfunction, essentially an inflammation of the lungs which results in chronic eathing difficulty. It is characterized by variable and recurring airflow obstruction secondary to mucous production by the respiratory epithelium and onchospasm. Airways are richly innervated by autonomic nervous system which play a part in the control and their secretion. They regu –late many aspects of airways’ physiology such as smooth muscle, mucus secretions, blood flow, micro vascular permeability and the migration and release of inflammatory cells. These effects are due OBSERVATIONS: In the present study, 32 patients (64%) were tested positive for autonomic dysfunction out of 50 cases. In < 5 yrs duration group, only 8 (40%) out of 20 cases had autonomic dysfunction, whereas in > 5 yrs. duration group, 24 (80%) out of 30 cases had autonomic dysfunction. Thus there was an increase in autonomic dysfunction with increased duration of asthma (p<0.05, significant). CONCLUSION: The duration of asthma also increases the incidence and severity of autonomic dysfunction. Thus it can be concluded that the incidence of autonomic dysfunction present in asthmatic patients increases with increasing duration of the disease emphasizing the role of autonomic nervous system in its patho physiology.