Correlation of histopathological changes in placenta in hypertensive disorders of pregnancy with perinatal outcome

Dr. Mohini Paul; Dr. Anam Ghani

Volume : IX, Issue : VIII, August - 2019

Correlation of histopathological changes in placenta in hypertensive disorders of pregnancy with perinatal outcome

Dr. Mohini Paul, Dr. Anam Ghani

Abstract :

HDP are known to complicate up to 10% of gestations and have become a major public health issue. The study was conducted in Kasturba Hospital in the Department of Obstetrics and Gynaecology, Delhi. The study consisted of 100 antenatal patients, 50 were normotensive (control) and 50 diagnosed with hypertensive disorders of pregnancy (cases). The term placenta were collected after delivery and examined for gross and histopathological changes. The findings were correlated with perinatal outcomes. The main gross features noted were calcification and infarction and main histopathological features were fiinoid necrosis, increased BM thickening, increased syncytial knotting, and stromal calcification. The increased incidence of these findings in HDP was found to be associated with adverse perinatal outcomes.