Volume : VIII, Issue : VII, July - 2018

CYTOGENETICS AND MOLECULAR STUDIES ON OLIGO/AZOOSPERMIA

Surya Sajikumar, Suchithra K R, Sanuj C Breezevilla, Dinesh Roy D

Abstract :

Infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8–12% of couples worldwide. Of all infertility cases, approximately 40–50% is due to “male factor” infertility and as many as 2% of all men will exhibit suboptimal sperm parameters. It may be one or a combination of low sperm concentration, poor sperm motility, or abnormal morphology. Hence the present study aimed to evaluate the cytogenetic and molecular studies on oligo/azoospermic subjects. Here 53 study subjects and twenty seven healthy control subjects were selected for cytogenetic and molecular studies. DNA damage was evaluated using Cytokinesis block micronuclei assay. Observations from the study analyze that study subjects were showed highest mean CBMN frequency than controls. Subjects with risk factors showed increased micronuclei frequency. Avoid modern lifestyle with regular exercise may to escape from male infertility.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Surya Sajikumar, Suchithra K R, Sanuj C Breezevilla, Dinesh Roy D, CYTOGENETICS AND MOLECULAR STUDIES ON OLIGO/AZOOSPERMIA, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-7 | July-2018

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