Detection of Hepatitis B Virus by Rapid and ELISA Test Methods and Their Comparison & Clinical Correlation in a Tertiary Care Hospital.

Dr Menka Khare; Dr Anil Kumar Singh

Volume : X, Issue : IV, April - 2020

Detection of Hepatitis B Virus by Rapid and ELISA Test Methods and Their Comparison & Clinical Correlation in a Tertiary Care Hospital.

Dr Menka Khare, Dr Anil Kumar Singh

Abstract :

Background: Hepatitis B can be a serious liver disease that results from infection with the Hepatitis B virus. Acute Hepatitis B refers to a short–term infection that occurs within the first 6 months after someone is infected with the virus. It can cause chronic liver disease and puts people at high risk of death from cirrhosis of the liver and liver cancer. The main objective of this study was detection of Hepatitis B Virus by Rapid and ELISA test methods and their comparison & clinical correlation in a tertiary care hospital. Methods: The present study was a cross sectional and comprised of all the clinical specimens of blood referred to microbiology laboratory from patient of all age groups that comes in Late Baliram Kashyap Memorial Govt. Medical College and hospital, Jagdalpur, Chhattisgarh. Duration of the study was from March 2019–May 2019. The study was conducted on 1250 clinical specimens. An informed written consent was obtained from all the patients who were enrolled. Results: Maximum no. of patients was from 21–30 years of age. The female to male ratio was 1.53:1. A clinical sample was more commonly from female patients. It was observed that (1.04%) samples were positive by rapid test and (98.96%) were negative by this rapid test. Conclusion: The rapid diagnostic test kit gives result in 20 minutes so that can be used in emergency situation. When there is need for testing of blood sample prior to apheresis procedure or when emergency blood issue needs to be done, rapid diagnostic test useful.