Determination of Acute and Chronic Urticaria Based on C–Reactive Protein or Mean Platelet Volume Levels

Duygu Erge; Ferat Catal; Erdem Topal; Elif Ozturk Senbaba; Nurdan Yildirim; Selcuk Inanoglu

Volume : V, Issue : IV, April - 2015

Determination of Acute and Chronic Urticaria Based on C–Reactive Protein or Mean Platelet Volume Levels

Duygu Erge, Ferat Catal, Erdem Topal, Elif Ozturk Senbaba, Nurdan Yildirim, Selcuk Inanoglu

Abstract :

 The aim of the present study is to investigate the relationships of mean platelet volume (MPV) and Creactive protein (CRP) levels in acute and chronic urticaria. We retrospectively evaluated 93 children with 

acute urticaria, 89 children with chronic urticaria and 103 healthy children as controls. Although MPV was found to be 

significantly higher in the chronic urticaria group than in the control group (median 7.5 vs. 7.15 fL, p < 0.05), CRP was 

significantly higher in children with acute urticaria (median 0.38 vs. 0.33, p < 0.05). No significant differences in platelet 

counts, platelet distribution width, mean platelet volume/platelet count ratio and neutrophil/lymphocyte ratio (p > 0.05) 

were found between urticaria patients and controls. Thus, acute and chronic urticaria may be discriminated by evaluating CRP and MPV levels before the end of 6 weeks in patients with urticaria.