Volume : VII, Issue : I, January - 2017

Dexamethasone or Clonidine � Which is the better additive to Local Anaesthetic for Supraclavicular Block ?

Dr Fijul Komu, Dr Bindu Meleveetil, Dr Radha K R, Dr Usha Kumari R, Dr Shiril Ashraf,

Abstract :

 Background: Brachial plexus block is an often used Regional Anaesthesia technique by the Anaesthesiologist either as an adjuvant to general anesthesia or as a sole anesthesia modality for upper limb surgeries. In view of prolonging the sensory block and duration of block, various adjuvants have been tried with varying degrees of success. Dexamethasone and Clonidine are two such adjuvants which has been found to be suitable as adjuvants in various studies. We compared the effect of dexamethasone or clonidine as adjuvants to local anaesthetic in supraclavicular achial plexus block in an effort to elicit the better adjuvant amongst both.   Methods:  This trial was conducted in a tertiary care centre on a group of fifty patients requiring elbow, forearm or hand surgeries. They were randomized into two groups of 25 each. Supraclavicular block was performed using nerve stimulator guidance. Group 1 received 20 ml 2% lignocaine with 1:200000 adrenaline and 10 ml 0.25% bupivacaine with  8mg dexamethasone. Group 2 received 20 ml 2% lignocaine with 1:200000 adrenaline and 10 ml 0.25% bupivacaine with 0.150 mg clonidine. The observed parameters were onset of sensory and motor blockade, the duration of analgesia and presence of any side effects. Data were subjected to statistical analysis using SPSS version 16. Students t test was used to analyse the quantitative variables. Qualitative variables were analysed using Chi square test. P < 0.05 was considered statistically significant.   Results: Mean onset of sensory block was 6.36+2.09 and 8.16+2.34 minutes in Group 1and Group 2 respectively. Mean onset of motor block was 8.16+2.17 and 9.96+2.45 minutes in Groups 1 and Group 2 respectively. Duration of analgesia in Groups 1 and Group 2 were 835.2+287.0 and 698.2+214.4 minutes respectively. No major side effects were noted in both the groups.   Conclusion: Dexamethasone may be a better additive to local anaesthetic than clonidine in supraclavicular block as it produces earlier onset of sensory and motor block. Longer duration of analgesia was also noted ,though the difference is not statistically significant in this study.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr Fijul Komu, Dr Bindu Meleveetil, Dr Radha K R, Dr Usha Kumari R, Dr Shiril Ashraf, , Dexamethasone or Clonidine � Which is the better additive to Local Anaesthetic for Supraclavicular Block ?, Indian Journal of Applied Research,Volume : 7 | Issue : 1 | JANUARY 2017

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