Volume : IX, Issue : I, January - 2019

Dexamethasone versus ondansetron in the prevention of postoperative nausea and vomiting in patients undergoing abdominal surgery under spinal anaesthesia: A randomized controlled trial

Harshitha Tayi, Syed Mohamed Shimar

Abstract :

Postoperative nausea and vomiting (PONV) is a common distressing symptom in patients undergoing elective abdominal surgeries. Reduction of incidence of PONV, by utilizing various antiemetic interventions, has been shown to improve patient satisfaction and reduce the time to recovery and discharge. METHODS: A Randomized control study was conducted in Yenepoya Medical College Hospital from October 2018 – November 2018. The study was conducted among 148 patients admitted for abdominal surgeries in the Yenepoya Medical College Hospital for period of one month. Before administering ondansetron or dexamethasone, blood pressure and heart rate of the patients were recorded. The patients received 70 mg of 5% lidocaine for spinal anesthesia. Patients who received 4 mg of ondansetron were considered as group O, while group D received 8 mg of dexamethasone. The level of nausea and vomiting, blood pressure, heart rate and respiratory rate of each patient was measured at 1, 5, 10, 15 and 30 minutes after spinal anesthesia. RESULTS: There was a significant difference between nausea and vomiting between the two groups of ondansetron and dexamethasone after spinal anaesthesia within the first and fifth minutes (p<0.05). There was no significant difference between nausea and vomiting between the two groups within 10, 15 and 30 minutes. There was no statistically significant difference between the mean levels of heart rate, systolic and diastolic blood pressures, respiration and oxygen saturation among both groups of ondansetron and dexamethasone CONCLUSION: Dexamethasone and ondansetron were equally effectively reducing the incidence of nausea and vomiting under spinal anesthesia and can be recommended for prevention of nausea and vomiting during surgeries using spinal anaesthesia

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DEXAMETHASONE VERSUS ONDANSETRON IN THE PREVENTION OF POSTOPERATIVE NAUSEA AND VOMITING IN PATIENTS UNDERGOING ABDOMINAL SURGERY UNDER SPINAL ANAESTHESIA: A RANDOMIZED CONTROLLED TRIAL, Harshitha Tayi, Syed Mohamed Shimar INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-1 | January-2019

Number of Downloads : 244

References :