Volume : VII, Issue : II, February - 2017

DIABETES MELLITUS AND RISK OF ENDOMETRIAL CARCINOMA

Dr. E. Vijayalakshmi, Dr . B. Tamilselvi

Abstract :

 Introduction: Cancer endometrium is now emerging as the most common female genital carcinoma . Exposure to higher levels of endogenous or exogenous estrogens plays a major role in endometrial carcinogenesis. Approximately 75% of endometrial carcinoma are postmenopausal and 25% premenopausal or perimenopausal

Aim: This  retrospective case study was undertaken to identify diabetes as a major  metabolic risk factor for endometrial cancer.

Materials & methods: This study was conducted at Govt ISO and Kasturba Gandhi Hospital for Women and Children, Madras Medical College ,chennai–05   on 44 cases of cancer endometrium confirmed histologically  for a duration  for 36 months(3yrs)  from January 2014 to December 2016.

 

Discussion & conclusion: This study shows a consistent positive association between diabetes and endometrial cancer almost two times risk exaggerated by obesity & sedentary habits four fold and finally 10 fold risk if all metabolic factors were present.. Interventions to reduce body weight and increase physical activity may have important implications in terms of prevention of endometrial cancer,also prompt and early  management of diabetic patients with proper diet and drugs and early diagnosis of cancer endometrium

 

 

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr.E.VIJAYALAKSHMI, Dr .B.TAMILSELVI, DIABETES MELLITUS AND RISK OF ENDOMETRIAL CARCINOMA, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾2 | February‾2017

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