Volume : VIII, Issue : IX, September - 2018

Diagnosis and Management of Gastrointestinal Stromal Tumors

Rayees Khanday, Ajaz Malik, Munir Wani, Zubaida Rasool

Abstract :

Introduction

Gastrointestinal Stromal Tumor (GISTs) are rare tumors of the gut which arise from interstitial cells of cajal1,2,3,4. They present with non–specific clinical feature. Diagnosis is done with the help of cross sectional imaging, Histopathological examination and Immunohistochemistry (IHC). Surgical resection is the treatment of choice. Imatinib is used in recurrent, metastatic and unresectable cases.

Materials and Methods

A total number of 50 patients were studied from 2013 to 2017. Preoperative diagnosis was made with the help of cross sectional imaging. Surgical excision was done as the primary treatment. Imatinib was given selectively in intermediate to high risk patients.

Results

Out of the 50 patients studied, definite preoperative diagnosis was made 32(64%) of the patients. Wide local excision (22%) was the most common surgical procedure, followed by wedge resection (20%) and distal gastrectomy (18%). Wound infection (6%) was the most common postoperative complication. Adjuvant treatment was given in 42% of the patients and recurrence occurred in 12% of the patients.

Conclusion

GISTs are rare tumors of the gut. Diagnosis is made with the help of CECT. Surgical excision is the treatment of choice. Imatinib is given in high risk patients.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Rayees khanday, Ajaz Malik, Munir Wani, Zubaida Rasool, Diagnosis and Management of Gastrointestinal Stromal Tumors, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-9 | September-2018


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