Volume : IX, Issue : III, March - 2019

Diagnostic accuracy of squash cytology in meningioma

Gopal Ravindran, Lalitha

Abstract :

BACKGROUND : Primary Central nervous system tumours occupies less than 2% of overall human cancers in adults. Among primary intracranial tumours , 20–30% are occupied by meningiomas. The accurate diagnosis of intracranial tumour is necessary for therapeutic and prognostic purpose. Intraoperative smear cytology provides a rapid diagnosis which helps the neurosurgeon for immediate decision regarding the extent of surgery. Objectives: To determine the accuracy of squash preparation, by compå it with histopathological sections and analysing the cytomorphological features of meningioma METHODS: This was both retrospective and prospective study. We received twenty radiologically and clinically suspected meningiomas in saline with fixatives. Crush smear were made and stained with rapid Haematoxylin and Eosin. The corresponding biopsy materials were fixed in 10% neutral buffered formalin and submitted for tissue processing. Staining was done with routine Haematoxylin and Eosin stain. The cytomorphologicalfeatures of these tumours were correlated with histopathological sections. Results:, In our study, we received twenty case of meningiomas,tissue of all the tumours were soft and easy to smear except a case of fious meningioma wich was relatively difficult to smear.Transitional meningioma was the most common histological type in our study , constituting 50% followed by meningothelialmeningioma (40%). We got 100% correlation between squash cytology and histopathology. Conclusion: Squash cytology is simple,rapid, accurate and cost effective diagnostic tool for meningioma

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DIAGNOSTIC ACCURACY OF SQUASH CYTOLOGY IN MENINGIOMA, Gopal Ravindran, Lalitha INDIAN JOURNAL OF APPLIED RESEARCH : Volume-9 | Issue-3 | March-2019

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