DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE OF CRP IN PAEDIATRIC SEPSIS

VAMSI KRISHNA. A

Volume : VI, Issue : VIII, August - 2016

DIAGNOSTIC AND PROGNOSTIC SIGNIFICANCE OF CRP IN PAEDIATRIC SEPSIS

Vamsi Krishna. A

Abstract :

Children aged above neonatal age group with clinically suspected sepsis as per the definition given by International Pediatrics sepsis consensus conference were enrolled in this prospective observational study. The CRP, white blood cell count and bands% were measured at the same time. One twenty– nine patients were enrolled in the study. Forty (31%) were culture proven sepsis and eighty nine (69%) were non culture proven sepsis. Respiratory tract infection was the most common source of sepsis (35%) followed by central nervous system infection (13%) and urinary tract infection (10%). CRP was better predictor of culture positive sepsis {Beta– 2.180 and P–0.005 (Exp B–8.8) 95% CI 1.94, 40.21}.A CRP cutoff point of 40mg/l was determined to maximize both sensitivity and specificity (sensitivity 90%, specificity 46.06%, and likelihood ratio 1.67, 95% CI: 1.34, 2.08)