Volume : VII, Issue : IX, September - 2017

Different presentations of Wilson disease in a tertiary care centre in South Tamil Nadu

Dr. Justin C, Dr. Sritharan B

Abstract :

 Wilson disease is an autosomal recessive disorder of copper metabolism. Diagnosis depends primarily on clinical features, biochemical parameters and the presence of the Kayser–Fleischer ring. Genetic analysis for mutations within ATP7B is a convincing diagnostic tool. The traditional treatment for WD includes chelation of excessive copper accumulation and reduction of copper intake. Medical therapy is effective but WD is not yet curable. Liver transplantation is especially helpful for patients who fail to respond to medical therapy or present with fulminant liver failure, although evaluation of its long–term effect are still in need.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Justin C, Dr. Sritharan B, Different presentations of Wilson disease in a tertiary care centre in South Tamil Nadu, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-7 | Issue-9 | September-2017

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