Volume : VIII, Issue : II, February - 2018

Distribution and Characterization of Candida Species in various Clinical samples at a Tertiary Care Hospital

Dr. Swati Salila

Abstract :

 

Background: Candida infections are becoming an increasingly important cause of morbidity and mortality in hospitalized patients. The increase in the incidence of Candida species over the past two decades is significant. Hence this study was to expand the yeast identification capabilities and to detect major pathogenic Candida species in different clinical samples.

 

Objectives: To determine the predominant Candida species in various clinical samples and phenotypic identification of various Candida species.

 

Materials and Methods: A hospital based observational cross–sectional study was conducted from October 2015 to June 2017 in the Department of Microbiology, Indira Gandhi Institute of Medical Sciences, Patna, Bihar.

 

Results: A total 106 samples were collected which mostly comprised of urine (57%) followed by blood (18%), HVS (10%), sputum (8%), pus (4%), oral swab (2%) and stool (1%). It showed dominance of non–albicans Candida spp. (71%) over Candida albicans (29%).The changing epidemiology of candida infection highlights the need for close monitoring of Candida species distribution and susceptibility to optimize treatment and outcome.

 

Conclusions: Invasive fungal infections seriously threaten the health of hospitalized patients, causing substantial morbidity, mortality, and increases in hospital costs. Therefore, early and accurate diagnosis of Candida infection is essential since each species varies significantly in susceptibility to the currently used antifungal drugs.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Swati Salila, Distribution and Characterization of Candida Species in various Clinical samples at a Tertiary Care Hospital, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-2 | February-2018

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