DRUG UTILIZATION STUDY OF RESTRICTED ANTIBIOTICS IN INTENSIVE CARE UNITS OF MCGANN DISTRICT TEACHING HOSPITAL, SHIVAMOGGA, KARNATAKA.

Sriti V Hegde; Anusha SJ; Chetan DB

Volume : X, Issue : VIII, August - 2020

DRUG UTILIZATION STUDY OF RESTRICTED ANTIBIOTICS IN INTENSIVE CARE UNITS OF MCGANN DISTRICT TEACHING HOSPITAL, SHIVAMOGGA, KARNATAKA.

Sriti V Hegde, Anusha Sj, Chetan Db

Abstract :

BACKGROUND: Drug utilization studies have very important value since it can help us to interpret, assess and improve prescribing patterns for diseases and ways to use medicine. OBJECTIVES: The objective of the study was to assess the prescription pattern and evaluation of restricted antibiotics’ usage in Intensive care units (ICUs) along with observation any adverse drug reactions. MATERIALS AND METHODS: After taking approval from Institutional Ethics Committee study was undertaken over a period of 6 months. A standard case record Performa was used to collect the demographic, clinical and drug prescription data of cases in the ICU who were prescribed restricted antibiotics. Its indication, dose, frequency and duration were entered. Data was analysed was done by using descriptive statistics. RESULTS: A total of 200 cases who were admitted in ICU’s were evaluated with mean age of 58.6. Average duration of stay in ICU was 4.52 days. Pneumonia (46%), septicaemia (23%), feile neutropenia (11%), intra–abdominal infections (8%) were common cases who were prescribed restricted antibiotics reported in ICU. Cephalosporins (52.22%) were commonly prescribed followed by Meropenem (19.4%) and Vancomycin (12.3%). Number of antimicrobials prescribed per patient was 1.54. In only 18% of the cases culture sensitivity test was performed. CONCLUSION: Optimum and appropriate use of antimicrobials has to be done in ICU to prevent multidrug resistance and to improve patients’ morbidity and mortality. The restricted antibiotics must be used after obtaining microbiological report only. Proper hospital or institutional antibiotic policy must be implemented for continuous monitoring of antimicrobial use to improve antibiotic prescribing.