Volume : VIII, Issue : IV, April - 2018

Early Diagnosis of Neonatal Sepsis - A Laboratory Challenge

Dr. Sourabh Mandwariya, Dr. Ashok Panchnia, Dr. C. V. Kulkarni

Abstract :

Sepsis in newborn is a divesting problem leading to morbidity and mortality. Inability to adequately exclude the diagnosis of neonatal sepsis can result in unnecessary and prolonged exposure of the newborn to antibiotics. Objectives of this study are to evaluate peripheral smears to establish an appropriate hematological parameter for early diagnosis of neonatal sepsis even before the blood culture.

We found that abnormal Total Neutrophil count is highly sensitive and increase Band cell count: Mature Neutrophil count ratio is highly specificfor early diagnosis of neonatal sepsis. The positive predictive value is highest for increase Band cell count: Mature Neutrophil count ratio (B:M)and negative predictive value is highest for abnormal Total Leukocyte count.Leukergy test is a good predictor for early diagnosis of neonatal sepsis. Group of Haematological parameters are more reliable indicator for early diagnosis of neonatal sepsis than any single parameter.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Sourabh Mandwariya, Dr. Ashok Panchnia, Dr. C. V. Kulkarni, Early Diagnosis of Neonatal Sepsis‾A Laboratory Challenge, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-4 | April-2018

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