IJAR - Indian Journal of Applied Research

Ramana Reddy V Moolagani; Shanker R Burla; Bhaskara R Neethipudi

Volume : IX, Issue : VII, July - 2019

Effect of a mixture of bupivacaine and lidocaine versus bupivacaine alone used for peribulbar blocks for cataract surgeries

Ramana Reddy V Moolagani, Shanker R Burla, Bhaskara R Neethipudi

Abstract :

Background : Mixtures of 0.5% bupivacaine and 2% lidocaine are commonly used in peribulbar blocks for cataract surgery. It is not clear whether 0.5% bupivacaine used alone can provide similar block characteristics and also whether the addition of adrenaline to bupivacaine will modify block characteristics. A prospective, randomized, double blind, parallel group study was conducted on a total of 80 patients with an aim to evaluate the peribulbar block characteristics using 0.5 % bupivacaine as a single agent (with or without adrenaline) versus mixture of 0.5% bupivacaine and 2% lidocaine (with or without adrenaline). Material and Methods : With computer generated random grouping software, patients were allocated to four groups of 20 each (n=20). Peribulbar block was given with eight ml of 0.5% bupivacaine and 0.02ml normal saline in group B, eight ml of 0.5% bupivacaine and 20 µg adrenaline in 0.02ml normal saline in group BA, four ml of 0.5% bupivacaine and four ml of 2% Lidocaine and 0.02ml normal saline in group BL and four ml of 0.5% bupivacaine and four ml of 2% lidocaine with adrenaline and 0.02ml normal saline in group BLA. Hyaluronidase 200IU was added to the anesthetic drugs for all the patients in the four groups. Data were analyzed in SPSS V22. Kruskal Wallis test and Chi–Square test were applied to find statistical significance. The P value of ≤ 0.05 was considered as statistically significant. Results: Onset of the block and duration of analgesia and the side effect profile were comparable in all the groups. Principle Conclusions: In peribulbar blocks 8.02ml of bupivacaine 0.5% used alone appears to be equally effective as that of a 8.02ml of 1:1 mixture of bupivacaine 0.5% and lidocaine 2%. Addition of adrenaline to the anesthetic agents had no statistically significant effect on block characteristics.