Volume : VIII, Issue : X, October - 2018

EFFECT OF AGE ON THYROID PROFILE IN CHRONIC KIDNEY DISEASE

Manpreet Saini, Gurpreet Kaur, Sona K. Gupta

Abstract :

 Aim:The aim of this study was to establish a correlation & find effect of Age on Serum T3,T4, TSH values of Chronic kidney disease patients.

Study Design:A hospital based Non–Experimental Observational Cross–sectional & Correlation Study was conducted on patients of both sex attending the Out Patient Department &In Patient Department of Nephrology & Medicine of SMI Hospital, P.Nagar Dehradun for a period of 4 months from January 2014 to April 2014. Study comprises 54 Chronic kidney disease patients which were divided into five age groups i–eAge group– 15–29yrs, Age group– 30–44yrs, Age group–45–59yrs, Age group– 60–74yrs, Age group– ≥75yrs. Inclusion criteria was patients with evidence ofChronic kidney disease selected randomly of both sex & age above 15 years. Exclusion criteria was age <15 years & those not willing to participate.

Methdology:Consecutive sampling technique &Bio–physiological method of collection of Data was used .5ml blood was collected in sterile tubes from the fasting (8–12hrs) test group & was analyzed for Serum T3, T4, TSH values by enzymatic method using VITROS ECIQ,an auto analyser at SMI Hospital,P.Nagar, Dehradun.Correlation coefficient i–e r–value& p–value was analysed using Microsoft office Excel 2007 .Positive r– value represented positive correlation between that age group & that parameter & vice versa.P<0.05 was considered significant & P<0.01was considered highly significant

Results:Age group 15–29yrs was found to have positive Correlation coefficient with S. T3, T4 & TSH values of Chronic kidney disease patients & there was significant(P<0.05) relationship of this age group with S. T3, T4,TSH values of Chronic kidney disease patients.

Age group30–44yrs was found to have negative Correlation coefficient with S. T3, T4 & positive Correlation coefficient with S. TSH values of Chronic kidney disease patients. Relationship of S.T3 & TSH was found to be Non significant (P>0.05) & S.T4 was found to have Highly significant (P<0.01) relationship with this Age group.

Age group 45–59yrswas found to have negative Correlation coefficient with S. T4,TSH& positive Correlation coefficient with S.T3 values of Chronic kidney disease patients. Relationship of S.T3,T4& TSH was found to be Non significant (P>0.05) with this Age group.

Age group 60–74yrs was found to have negative Correlation coefficient with S. T3 & positive Correlation coefficient with S. T4 & TSH values of Chronic kidney disease patients. Relationship of S.T3,T4& TSH was found to be Non significant (P>0.05) with this Age group.

Age group ≥75yrs was found to have negative Correlation coefficient with S. T3,T4& positive Correlation coefficient with S. TSH values of Chronic kidney disease patients. Relationship of S.T3,T4& TSH was found to be Non significant (P>0.05) with this Age group.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Manpreet Saini, Gurpreet Kaur, Sona K.Gupta, EFFECT OF AGE ON THYROID PROFILE IN CHRONIC KIDNEY DISEASE, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-10 | October-2018

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