EFFECT OF ALOE VERA EXTRACT AND ISONIAZID –RIFAMPICIN DRUG ON MYCOBACTERIUM TUBERCULOSIS BACTERIAL (MTB) STRAIN –H37Rv

Zodape G. V.; Bhise P. P.

Volume : VII, Issue : VII, July - 2017

EFFECT OF ALOE VERA EXTRACT AND ISONIAZID –RIFAMPICIN DRUG ON MYCOBACTERIUM TUBERCULOSIS BACTERIAL (MTB) STRAIN –H37Rv

Zodape G. V. , Bhise P. P.

Abstract :

Many researchers have performed the experiments on several plants to investigate the effect of plant extract against different Mycobacterium strains. In view of the above cited claims, the present study was undertaken to screen the Aloe vera plant extract for its antitubercular activity in vitro. This experimental work would serve as baseline model system to establish new templates in the bioprospection and development of new and more effective pant – based antibiotics. This study was conducted to find the direct effect of drugs RIF– INH and Aloe vera extract individually as well as in combination with drugs and Aloe vera on micobacterial strain H37Rv and we found that while using Aloe vera extract, it does not affect the activity of antitubercular drug RIF and INH either individually or in combination. It was also found that Aloe vera extract alone seems to have antimicobacterial activity in some extent.