EFFECT OF ANTE RETROVIRAL THERAPY ON CD4 COUNT IN PEOPLE LIVING WITH HIV/AIDS

Dr.Mukund Bhaskarrao Kulkarni; Dr.Muktpal Marotrao Bhalerao

Volume : IX, Issue : IV, April - 2019

EFFECT OF ANTE RETROVIRAL THERAPY ON CD4 COUNT IN PEOPLE LIVING WITH HIV/AIDS

Dr. Mukund Bhaskarrao Kulkarni, Dr. Muktpal Marotrao Bhalerao

Abstract :

The most important immune marker in the HIV infection or AIDS is CD4+T Lymphocyte (CD4).CD4 cells are the most important element of the cell mediated immunity in human being. ‘Highly Active Ant Retroviral Therapy’ (HAART) or ART has changed the HIV/AIDS from a ‘virtual death sentence’ to a ‘chronic manageable disease’ Aim and Objectives: Aim of our study to find the effect of ART on immunity status particularly on CD4 count in PLWH on ART as compare to those who are not on ART. Materials and Methods: Two hundred PLWH of age group 18–60 years were included in the study Study conducted at tertiary care hospital and medical teaching institute in India. CD4 count is carried out by flow cytometry. CD4 count done on Partec ™ cyflow counter Germany. Results: The results of study found 40.11% of the subjects on ART had CD4 count > 500 as compared to only 21.22% of subjects who were not on ART. Significant relation in ART and CD4 count observed (p=0.001). Conclusions: ART increase CD4 count in PLWH increasing immunity and improving health.