Effect of Cilostazol on Ischaemic wound size

Dr Manonmani M H; Dr Raman M Hulinaykar

Volume : VI, Issue : XII, December - 2016

Effect of Cilostazol on Ischaemic wound size

Dr Manonmani M H, Dr Raman M Hulinaykar

Abstract :

Introduction: Ischaemic wounds accounted for a substantial threat to a patient‘s quality of life. There is a need for agents which would aid in the faster healing of these ulcers and improve the quality of living of these individuals and also reduce the burden on the health care system. As newer drugs are released in the market, interest has grown in the feasibility of use of cilostazol in the treatment of ischaemic wounds and to hasten the healing process. Methods: 3 week administration of tab. Cilostazol 100mg twice daily in patients. Ulcer healing was measured and standardized by marking on tracing sheets. To assess the area on the tracing paper, the major diameter is multiplied by the major orthogonal diameter. Results: The mean duration of ulcer before the treatment with cilostazol was 13 months. We observed changes in the characteristics of ischemic wound when it is responding to cilostazol. Wound becomes redder and appears more vascular in nature, the necrosis starts ceasing and wound begins heal. The mean percentage improvement in the area of ulcer after treatment with cilostazol is 45.95%. Conclusion: Cilostazol was found to have potentiated the wound healing rate of ischemic ulcer. Although cilostazol is somewhat expensive, it appears to be more helpful in alleviating claudication and improving wound healing rate as useful adjunctive therapy