Effect of commercially available Generic and Ethical drugs against isolated uropathogenic Escherichia: A study

Dr. Sandhya Tambekar

Volume : X, Issue : I, January - 2020

Effect of commercially available Generic and Ethical drugs against isolated uropathogenic Escherichia: A study

Dr. Sandhya Tambekar

Abstract :

The resistance pattern of uropathogens is increasing very rapidly because of the unsorted, insufficient and incoherent usage of antibiotics. Urinary tract infection (UTI) is considered as a different type of infection which is caused by the uropathogenic resistant bacteria. This infection is due to the main colonization of normal and opportunistic microflora. The rate of UTI patients is high due to poor hygiene, long time catheterization, uncontrolled sexual intercourse, pregnancy and spermicidal contraception. The present study deal with effect of Generic and Ethical drugs on uropathogenic Escherichia species isolated from urine samples. In present study, total 50 samples were collected from five pathology laboratories in Gondia City to isolate Uropathogenic Escherichia coli. However, only 44 Escherichia spp. were isolated from collected urine samples. On the basis of morphological, cultural and biochemical characteristics, isolates were identified as Escherichia. It is evident from the data that 100% Escherichia spp. isolated from urine samples were sensitive to both ethical and generic Levofloxacin whereas 88.6% Escherichia spp. isolated from urine samples were resistant to both ethical and generic Amoxicillin trihydrate after 24 – 48 hrs incubation. Using generic drug is more economic than ethical drug because it reduces burden of high cost of ethical drugs on patients and lowers their expense on medicine.