Volume : V, Issue : V, May - 2015

EFFECT OF ÃŽ�‚±–CYCLODEXTRIN ON GEFITINIB

A. Glory Punitha, Dr. J. Prema Kumari

Abstract :

 Gefitinib is a drug used in the treatment of metastatic epethilial cell lung cancer. This Study  examined the complexation of Gefitinib with α–Cyclodextrin in liquid State. The inclusion processes are discussed based on absorption, emission and phase solubility studies. The absorption and emission maxima of gefitinib appear at 263nm and 402nm. The stability constant [Kst] of Gefitinib is calculated..  The formation constant [K] value is calulated by analysing in the intensities of absorption and emission  maxima with the α–CD concentration.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

A.Glory Punitha, Dr.J.Prema Kumari EFFECT OF ÃŽ�‚±�CYCLODEXTRIN ON GEFITINIB Indian Journal of Applied Research, Vol.5, Issue : 5 May 2015

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