Volume : VIII, Issue : III, March - 2018

EFFECT OF ESMOLOL INFUSION ON QUALITY OF EXTUBATION IN PATIENTS UNDERGOING GENERAL ANAESTHESIA

Dr. R. Ganesapandian, Dr. Srinidhi. V

Abstract :

 

Mechanical stimulation of the receptors present in the larynx, trachea results in both respiratory and cardiovascular reflex responses during intubation. Heart rate is a major determinant of myocardial oxygen consumption and cardiac workload, so decreasing the heart rate will increase the ischemic threshold and improve the cardiac performance Aim: evaluation of the effect of esmolol infusion on quality of extubationin patients undergoing general anaaesthesia   Methodology: A prospective study including 100 patients undergoing elective surgeries under general anaesthesia. Group E (esmolol) 0.5mg/kg bolus dose over 30 s starting 5 min before intubation.   0.5mg/kg bolus dose over 30 s followed by a continuous  esmolol infusion of 100 microgm/kg/min starting 10 min before end of surgery till  5 min after extubation  Group C received saline  as above, loading dose followed  by same volume of infusion.The parameters monitored  were Post–operative nausea and vomiting No. of doses of antiemeticin the first 24 hr of surgery and  Quality of extubation Results: Our study showed reduced incidence of post–operative nausea and vomiting in Group E(esmolol) when compared with control group. Patients in group E had a better quality of extubation with low incidence of cough, laryngospasm when compared to the control group Conclusion: esmolol is a safe, effective drug that can be used in patients undergoing general anaesthesia with low post operative nausea and vomiting and better quality of extubation

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

DR.R.GANESAPANDIAN, Dr.SRINIDHI.V, EFFECT OF ESMOLOL INFUSION ON QUALITY OF EXTUBATION IN PATIENTS UNDERGOING GENERAL ANAESTHESIA, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-3 | March-2018

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