Volume : VIII, Issue : VIII, August - 2018

EFFECT OF ESMOLOL ON THE INDUCTION DOSE OF PROPOFOL

Sadhan Sawhney, Saurabh Sud, Deepak Dwivedi, Josemine Davis

Abstract :

Induction, laryngoscopy and endotracheal intubation are an integral part of general anaesthesia. It leads to cardiovascular stress response. To avoid the rise in heart rate and mean blood pressure large doses of propofol during induction, are required to be given which are associated with complications. To prevent these complications various drugs like midazolam, dexmedetomidine, opioids are given along with propofol, which is supposed to decrease the total dose of propofol needed for induction. Esmolol which is β1–adrenergic receptor antagonist is known to decrease the rise in heart rate and mean blood pressure. This prospective randomised double blind study was planned to compare the effect of esmolol on induction dose of propofol on the patients undergoing surgeries. A total of 100 eligible patients were divided randomly into two groups, Group P (Propofol n=50), Group E (Esmolol n=50). Results showed that esmolol was able to reduce the total induction dose of propofol by 18.5%.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Sadhan Sawhney, Saurabh Sud, Deepak Dwivedi, Josemine Davis, EFFECT OF ESMOLOL ON THE INDUCTION DOSE OF PROPOFOL, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-8 | Issue-8 | August-2018

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