Volume : III, Issue : XII, December - 2013

Effect of imidacloprid on plasma and tissue biochemistry of albino rat

Prerna Vohra, Kuldeep Singh Khera

Abstract :

Imidacloprid was given orally to female albino rats for 60 days. Rats were divided into three groups. The control animals (first group) were given corn oil. Second group treated with 1/45th LD50 of imidacloprid and third group with 1/22th LD50 of imidacloprid to assess the alterations in the level of some biochemical prameters in tissues. Liver alanine aminotransferase (ALT), aspartate aminotransferase (AST) increased significantly at high dose of imidacloprid. Acid phosphatase (ACP) and alkaline phosphatase (AKP) activity increased significantly at 1/22th LD50 of imidacloprid in liver and ovary. Significant decrease was observed in plasma 3β– hydroxysteroid dehydrogenase (3β HSDH) activity at 1/22th LD50 of imidacloprid. Histological examination of ovary of 1/22th LD50 of imidacloprid showed atretic follicles. Imidacloprid at 1/22th LD50 was found to be toxic to rats.

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Prerna Vohra, Kuldeep Singh Khera Effect of imidacloprid on plasma and tissue biochemistry of albino rat Indian Journal of Applied Research, Vol.III, Issue.XII Dec 2013

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