Effect Of Intramyometrial Injection Of Vasopressin In Reducing Blood Loss During Caesarean Section In Placenta Praevia: A Comparative Study

Dr SAMIMA JESMIN ALI; Dr PALLAB KUMAR MISTRI

Volume : X, Issue : IV, April - 2020

Effect Of Intramyometrial Injection Of Vasopressin In Reducing Blood Loss During Caesarean Section In Placenta Praevia: A Comparative Study

Dr Samima Jesmin Ali, Dr Pallab Kumar Mistri

Abstract :

INTRODUCTION: In a patient complicated by placenta praevia, profuse haemorrhage may occur following separation of placenta during caesarean section. Sometimes, hysterectomy with massive blood transfusion may be required to save the mother. The reduction of blood loss may be achieved following vasopressin injection into the placental implantation site. MATERIALS AND METHODS: In our study with sample size 60, 20 units of vasopressin diluted in 100 ml of normal saline were injected in the placental site in 30 patients with placenta praevia during caesarean section. The outcome was measured and compared with control group. RESULTS: Bleeding was successfully arrested with a mean volume of blood loss being 1114.6 ml in the study group whereas in the control group, mean volume of blood loss being 1367.33ml (p=0.0016). None of them exhibited any adverse effect and did not require haemostatic surgical sutures or hysterectomy. CONCLUSION: The intramyometrial diluted vasopressin in the placental bed following placental separation during cesarean section in cases of placenta previa effectively reduced and arrested blood loss without any adverse effects