Volume : V, Issue : III, March - 2015

Effect of Methyl Parathion on TSH, T4 And T3 in Fish, Labeo Rohita

S. N. C. Ray, Chandra Mohan, R. C. Sinha

Abstract :

Pesticides are often used indiscriminately, in large amount causing environmental pollution. Pesticides cause adverse effects on different body systems, including endocrine system. Many authors have reported the ability of organophosphate pesticides to disturb thyroid function. The aim of this work was to investigate the effect of sub–acute toxicity on TSH, T4 and T3 in the fish Labeo rohita. The acute toxicity (L50 96 h) was 16.8 ppm for methyl parathion and the fish was exposed to 1/3rd of LC 96 h. (5.6 ppm). TSH decreased by 42.6% in 24 h but increased by 303.9% and 76.5% during 48 & 72 h and then decreased during 96 h by 11.8%. T3 decreased by 82.2, 56.8, 19.2 and 61.7% in 24, 48, 72 and 96 h respectively than the control. T4 decreased by 7.2, 13.4 during 24 and 48 h respectively, but increased by 41.6% to that of 48 h in 72 h. The sub–lethal toxicity which cause decrease in serum T3 & T4 and TSH may be due to the reduction in fish metabolic rate, indirectly reducing the toxic impact of the pesticides. During pesticidal exposure, for regaining safe homeostasis fish perform many physiological processes and the two important physiological processes which are modulated when fishes are exposed to stress are the hormonal status and immune functions. Suppressed level of thyroid hormones found in Labeo rohita depicts physiological stress

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

S. N. C. Ray, Chandra Mohan, R. C. Sinha Effect of Methyl Parathion on Tsh, T4 And T3 in Fish, Labeo Rohita Indian Journal of Applied Research, Vol.5, Issue : 3 March 2015

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