Volume : VII, Issue : XI, November - 2017

EFFECT OF ORMELOXIFENE ON HAEMOGLOBIN STATUS IN ABNORMAL UTERINE BLEEDING

Dr. P. Geetha Kumari, Dr. S. Anuradha

Abstract :

 AIM  :

            Abnormal Uterine Bleeding (AUB) is the commonest presenting symptom in Gynaecology out– patient department. The Aim is to study the efficacy, safety and acceptability of ORMELOXIFENE in improving Haemoglobin concentration in patients with Histopathological reports like Secretory phase, Proliferative phase, Late Proliferative phase and Surface Hyperplasia in AUB. We also tried to observe the Incidence of various pathologies in different age groups presenting with AUB,AUB being the major contribution to anaemia, non–surgical management of the problem should be the main stay of treatment.

 

Methods:

This is a Hospital based Prospective study which included a sample size of 50.50 cases of AUB were observed. Each patient was given 60 mg. of Ormeloxifene twice weekly (Sunday &Wednesday) for a period of 3 months and then weekly once (Sunday) for another 3 months. Primary outcome measures were menstrual blood loss, Haemoglobin concentration and Histopathological type.

 

Results :

The Mean post treatment HB concentration and PBAC for was significantly increased. 

 

 

 

 

Conclusion:

Ormeloxifene is safe and effective drug for medical management of AUB.It is non–steroidal, pharmacologically and metabolically safe, oncologically protective and cost effective too.

Keywords :

Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. P. Geetha Kumari, Dr. S. Anuradha, EFFECT OF ORMELOXIFENE ON HAEMOGLOBIN STATUS IN ABNORMAL UTERINE BLEEDING, INDIAN JOURNAL OF APPLIED RESEARCH : Volume-7 | Issue-11 | November-2017

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