Effect of TheTotal Lycium barbarum Carotene on Normal Human Blood Lymphocytes

Dr.Zainab Yaseen Mohammed

Volume : V, Issue : XII, December - 2015

Effect of TheTotal Lycium barbarum Carotene on Normal Human Blood Lymphocytes

Dr. Zainab Yaseen Mohammed

Abstract :

The discovery and identification of a new drugs, which can potentiate the immune function has become an important goal of researches in immune–pharmacology and oncotherapy. This study demonstrates the favorable effects of Iraqi wild type Lycium barbarum active components as immunomodulating agent. The immune stimulating effect of the extracted total carotene showed normal blood lymphocytes proliferation estimated by MTT assay and alteration in IL–10 and TNF–α level by ELISA technique caused both cytokines level elevation after 2 and 4 hours exposure at concentrations .The result of the present study indicated that Lycium Carotenoids as pigments responsible for the red, orange and yellow coloration of plants, can behave as an immunostimulants, acted to promote IL–10 production and increase TNF–α level specially at lower concentration(125µg/ml) after 2 hours of exposure about four folds of their normal TNF–α level.