Volume : VII, Issue : III, March - 2017

Effect of topical 0.05% cyclosporine for the treatment of vernal keratoconjunctivitis

Dr. Dipali Satani, Dr. Krupali Raol, Dr. Shwetambari Singh

Abstract :

 BACKGROUND: To evaluate the short–term efficacy and safety of topical 0.05% cyclosporine for patients with vernal keratoconjunctivitis. METHODS: Fifteen patients with severe vernal keratoconjunctivitis were included in the study. All were treated with 0.05% cyclosporine eye drops. Eyes that received cyclosporine eye drops did not receive any other eye drops except 0.5% luicating (CMC) eye drops. Symptoms and signs were scored on the day of enrolment and at the end of days 1, 2, 7,14,30,60,90,120,150 and 180. RESULTS: At the end of 7 days, no statistically significant decrease was noted from baseline in mean scores of either signs (p = 0.18) or symptoms (p = 0.50) in the eyes that received cyclosporine. On the other hand, a statistically significant decrease was observed in both sign and symptom scores (p < 0.001, for both) of eyes that received cyclosporine at the end of 14 days. At days 30 and 90, statistically significant decrease in both sign scores and symptom scores were noted compared with baseline in the eyes that received cyclosporine eye drops (p < 0.001, for all).

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Article: Download PDF   DOI : 10.36106/ijar  

Cite This Article:

Dr. Dipali Satani, Dr.Krupali Raol, Dr. Shwetambari Singh, Effect of topical 0.05% cyclosporine for the treatment of vernal keratoconjunctivitis, INDIAN JOURNAL OF APPLIED RESEARCH : Volume‾7 | Issue‾3 | March‾2017

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