Effect of Treatment on Immune Status of Patients  with Head and Neck Cancer

Kereena Chukka; Prof. Z. Vishnuvardhan; Prof. S. Krupanidhi

Volume : III, Issue : VIII, August - 2013

Effect of Treatment on Immune Status of Patients with Head and Neck Cancer

Kereena Chukka, Prof. Z. Vishnuvardhan, Prof. S. Krupanidhi

Abstract :

Malnutrition, head and neck cancer, and surgery are all associated with impaired immune function, especially with regard to cellular immunity. The present study was initiated to assess the effect of treatment on immune status of patients with head and neck cancer. For this study 15 head and neck cancer patients with the group ranging from 30 to 60 years of both the sex were selected from department of Radiotherapy, Government General Hospital, Guntur, India. The blood samples were analyzed for Biomarkers (CD3, CD4, CD45, CD3% & CD4%) before and after treatment. There is no difference between before and after treatment in immune status of head and neck cancer cases. In the present study the investigator unable to show any noticeable immunologic differences between before and after treatment. Along with treatment immune boosters (Nutritional supplements) may be benefit via stimulating components of immune function, nitrogen balance and wound healing. A large patient cohort with a longer follow up period for therapeutic response studies may yield more significant.