Effects of Piper Betel AQUEOUS EXTRACT ON ELECTROPHORETIC PROTEIN IN SEMEN OF MALE MICE

AARTI VERMA*; V.N.SINGH

Volume : VI, Issue : VI, June - 2016

Effects of Piper Betel AQUEOUS EXTRACT ON ELECTROPHORETIC PROTEIN IN SEMEN OF MALE MICE

Aarti Verma , V. N. Singh

Abstract :

  The present study shows that the effects of Piper betel leaf stalk aqueous extract was administered orally at the dosage of 0.15ml(50mg/kg/BW/day) on male mice for 50 days. This treatment causes significant increased in total electrophorectic protein concentration in seminal plasma of mice collected from cauda epididymis during 10, 20 (P<0.01), 30, 40 and 50 (P<0.001) of treatment than control. Significant increase in electrophoretic protein concentration causes increase in viscosity of seminal plasma of Piper betel leaf stalk treated mice that result into low motility and high mortality rate of spermatozoa. Piper betel leaf stalk treated mice shows rise in anodic protein concentration which adds more negative charges on sperm surface memane that inhibits capacitation and fertilizing capability of the sperm. This suggests that Piper betel leaf stalk shows antifertility effects in male mice by increasing viscosity of semen plasma causing lower motility and also impair capcitation of spermatozoa, thus helps in fertility control.